| Kāpēc šķiedrvielas ir svarīgi. |
[Jun. 25th, 2024|07:57 pm] |
Introduction: Tryptophan is catabolized by gut microorganisms resulting in a wide range of metabolites implicated in both beneficial and adverse host effects. How gut microbial tryptophan metabolism is directed towards indole, associated with chronic kidney disease, or towards protective indolelactic acid (ILA) and indolepropionic acid (IPA) is unclear.
Methods: Here we used in vitro culturing and animal experiments to assess gut microbial competition for tryptophan and the resulting metabolites in a controlled three-species defined community and in complex undefined human faecal communities.
Results: The generation of specific tryptophan-derived metabolites was not predominantly determined by the abundance of tryptophan-metabolizing bacteria, but rather by substrate-dependent regulation of specific metabolic pathways. Indole-producing Escherichia coli and ILA- and IPA-producing Clostridium sporogenes competed for tryptophan within the three-species community in vitro and in vivo. Importantly, fibre-degrading Bacteroides thetaiotaomicron affected this competition by cross-feeding monosaccharides to E. coli. This inhibited indole production through catabolite repression, thus making more tryptophan available to C. sporogenes, resulting in increased ILA and IPA production. The fibre-dependent reduction in indole was confirmed using human faecal cultures and faecal-microbiota-transplanted gnotobiotic mice.
Conclusion: Our findings explain why consumption of fermentable fibres suppresses indole production but promotes the generation of other tryptophan metabolites associated with health benefits.
https://www.nature.com/articles/s41564-024-01737-3
Triptofāns ir serotonīna prekursors. Šķiedrvielas ir antidepresants. (Tā es tikko izdomāju) |
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[Jun. 23rd, 2024|01:47 pm] |
"A new report has shed light on the relationship between antibiotic-resistant bacteria, superbugs, and animal farming, particularly on factory farms. The report, published by World Animal Protection, has revealed that UK rivers and waterways are “awash with superbugs.”
Specifically, waterways adjacent to factory farms and “high welfare” outdoor farms were found to contain antibiotic-resistant strains of E. coli and Staphylococcus aureus, both of which can cause serious health complications in humans.
The overprescription of antibiotics in medical settings since the drugs were first introduced has led to a sharp uptick in resistant bacteria. Animal agriculture’s misuse of such medications has further exacerbated the issue.
Superbugs are strains of bacteria, viruses, and parasites that are resistant to most widely used antibiotics. This can lead to more severe cases of potentially preventable illnesses, as well as infections that cannot be treated with medication.
Examples include drug-resistant salmonella, campylobacter, tuberculosis, and gonorrhea. The Centers for Disease Control and Prevention (CDC) says antimicrobial resistance is an “urgent global public health threat.”" |
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| Izskatās, ka nākotnē lielāko daļu elektroenereģijas, ko lietos visā pasaulē, saražos saule. |
[Jun. 21st, 2024|04:26 pm] |
Tā viš ir, tepat dažu gaismas minūšu attālumā ir milzīgs reaktors, kurš nerimstoši raida enerģiju, ko mums lietot. Var izdomāt visvisādus iemeslus kāpēc ne, bet rādās, ka nepielūdzami nāksies vien to darīt. Kas arī šķiet loģiski, ņemot vērā cik strauji attīstās saules paneļu efektivitāte un pazeminās to cena.
Ļoti iespējams, ka drīz vien Āfrika sāks ļoti strauji attīstīties, jo tai uzradīsies milzīgs apjoms superlētas elektroenerģijas. Esmu optimisma pilns. Vēl tikai tāds sīkums kā efektīvāki veidi kā uzglabāt enerģiju, bet zinot, cik ļoti homo sapiens ir spējīgs attīstīt un uzlabot jau esošas tehnoloģijas, ilgi nebūs jāgaida. Aiziet!
https://www.economist.com/leaders/2024/06/20/the-exponential-growth-of-solar-power-will-change-the-world
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| Man arī rieksti vienmēr ir šķituši stipri nediētisks, kalorijām bagāts uztura avots. |
[Jun. 19th, 2024|02:14 pm] |
"But in fact, nuts are rich in healthy unsaturated fats, plant protein and dietary fibre, all of which play a role in promoting satiety, and reducing excess calorie consumption. Nuts are associated with improved cardiovascular and metabolic health, better gut health and enhanced cognitive performance."
https://www.unisa.edu.au/media-centre/Releases/2024/weight-loss-go-nuts-or-go-home/ |
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[Jun. 19th, 2024|12:16 pm] |
Ne tas saldākais avots, bet ..
" A surprising range of creatures have shown evidence of conscious thought or experience, including insects, fish and some crustaceans.
That has prompted a group of top researchers on animal cognition to publish a new pronouncement that they hope will transform how scientists and society view — and care — for animals."
https://www.yahoo.com/news/scientists-push-paradigm-animal-consciousness-151744245.html |
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| Dienas citāts no reddita dzīlēm. |
[Jun. 19th, 2024|10:21 am] |
"Processed meats (ham, pork sausage, bacon, etc.) are class 1 carcinogens, meaning they cause cancer. Red meats (pork, beef, lamb, etc.) are class 2A carcinogens, meaning they probably cause cancer."
"Red meats, including pork, are group 2A "probable" carcinogens. The mechanism is known: heme iron. It catalyzes carcinogenic N-nitroso compounds and cytotoxic aldehydes."
https://www.who.int/news-room/questions-and-answers/item/cancer-carcinogenicity-of-the-consumption-of-red-meat-and-processed-meat |
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| Divas tradicionālas vērtības. |
[Jun. 18th, 2024|11:52 am] |
Mobings un viktimbleimings. |
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| Dienas citāts no reddita dzīlēm. |
[Jun. 18th, 2024|07:28 am] |
"From what I see nuclear tech can solve a lot of problems, like eliminating large corporations, decreasing overall temperature and(in some cases) decreasing population density. Im just saying, nuclear weapons are usefull." |
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| Mazliet par melnu, bet nu eu! |
[Jun. 17th, 2024|08:04 pm] |
Lai gan no otras puses, indējot odus, noindēs sevi un beigs indēt visu dzīvo.
"Is allethrin harmful to humans?
Toxic by ingestion, inhalation, and skin absorption. A synthetic household insecticide that kills flies, mosquitoes, garden insects, etc." |
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| Nīkuļi, |
[Jun. 17th, 2024|02:31 pm] |
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īstiem vīriem kleitās pat plakstiņš nenoraustās, kad mazulītes nolaižas uz miesas asintiņu nodzerties. |
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[Jun. 17th, 2024|01:43 pm] |
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Skatos šogad populāri ir elpot insektocīdus. Kā arī nogalināt visus kukaiņus savā perifērijā, kas tālāk? |
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[Jun. 13th, 2024|08:03 pm] |
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| Citāts no reddita dzīlēm. |
[Jun. 11th, 2024|02:19 pm] |
"For endurance sports aging (initially) can be beneficial because you lose muscles and you become more efficient. That's why (historically, before modern training) endurance athletes (marathon runners/gc riders) would peak around 32/33. Heck, kipchoge is going for gold in Paris at 40!" |
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[Jun. 11th, 2024|10:56 am] |
Iedod cilvēkam zivi un viņš būs paēdis, iemāci cilvēkam zvejot, un viņš iztukšos un piedirsīs visus pasaules okeānus.
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