> As the production of these NNAbs produced upon VBTIs in highly C-19 vaccinated populations will soon collectively decrease to suboptimal levels, SC-2 is poised to undergo a spectacular mutation to overcome the immune selection pressure collectively exerted by these Abs on the virus's capacity to prevent their virulence-inhibiting activity. This strongly suggests that in populations with high C-19 vaccination rates, elevated infection rates may no longer come with the benefit of protection against severe C-19 disease.
> The unexpected emergence of Omicron and its significant mutational changes in the receptor-binding domain of S protein (S-RBD) has caught us all off guard. The advent of Omicron was a scourge as it paved the way for the imminent appearance of a new variant, only expected to emerge much more suddenly and come with mutations (presumably in the O-glycosylation profile) that are even much more spectacular. Unlike the previous situation with the advent of Omicron, the consequence this time will not be limited to heightened infectiousness but will be compounded by a high level of viral virulence.
#spectacular #spank-spank #naughty #hujovids
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