A Chelsea - CFR Cluj
A Roma - Bordeaux 2-0
B Panathinaikos - Anorthosis 0-1
B Bremen - Internazionale 1-2
C Basel - Sporting 0-0
C Barcelona - Shakhtar 3-1
D PSV - Liverpool 0-1
D Marseille - Atlético 1-2

Matchday 6 - 10 December 2008
Group Home Away
E Man. United - AaB 3-0
E Celtic - Villarreal 1-0
F Steaua - Fiorentina 0-2
F Lyon - Bayern 2-2
G Porto - Arsenal 1-1
G Dynamo Kyiv - Fenerbahçe 0-0
H Juventus - BATE 2-0
H Real Madrid - Zenit 2-1