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Perhaps the best-known contemporary case is that of Viagra, which was originally tested as a treatment for angina. It was almost immediately found to be less effective than nitroglycerine for coronary artery dilatation, but then the patients in the first clinical trial reported an unusual, not at all undesirable and now well-known side effect. It is no wonder that the patients became depressed when the first clinical trials were brought to an end, and it was requested that the unused pills be returned to Pfizer. The company noted that never had so many unused clinical trial pills been reported as lost, misplaced, or accidentally flushed down the toilet...
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