A Chelsea - CFR Cluj 3-0
A Roma - Bordeaux 2-1
B Panathinaikos - Anorthosis 2-0
B Bremen - Internazionale 1-1
C Basel - Sporting 0-3
C Barcelona - Shakhtar 2-1
D PSV - Liverpool 2-2
D Marseille - Atlético 3-1

Matchday 6 - 10 December 2008
Group Home Away
E Man. United - AaB 3-1
E Celtic - Villarreal 2-0
F Steaua - Fiorentina 1-2
F Lyon - Bayern 3-2
G Porto - Arsenal 2-2
G Dynamo Kyiv - Fenerbahçe 1-3
H Juventus - BATE 3-1
H Real Madrid - Zenit 2-0