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May. 20th, 2021|09:27 am |
iecheko ADE (non-neutralizing antibodies) ...
https://www.medrxiv.org/content/10.1101/2021.03.07.21253098v2
(".. there is the phenomenon of antibody-development enhancement (ADE). ADE means in addition to the usual way, the virus may get into our bodies by binding with non-neutralizing antibodies. Rather than fighting the virus, these antibodies, as the name says, enhance it.
"Neutralizing antibodies afford a protective effect against virus entry into the host cells. On the other hand, the antibodies generated against the non-neutralizing epitopes could enhance virus entry leading to severe disease outcomes."
And even low levels of non-neutralizing antibodies can "enhance virus entry and worsen the disease outcome." |
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