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[24. Apr 2015|23:36]

mindbound
[Tags|, , , ]
[Garastāvoklis: |tired]
[Mūzika |Empusae - Error 404: Alkevar]

A sign that one is exhausted: Consistently misreading "Fremen" instead of "firemen".
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[24. Apr 2015|23:07]

mindbound
[Tags|, , , , , , , ]
[Garastāvoklis: |working]
[Mūzika |Alcest - Les Voyages De L'Âme: Nous Sommes L'Émeraude]

Thomas Ligotti's works would probably go brilliantly with Bloodborne (too bad I won't be having a PS4 in the near future, if only for that game).

The sinister, the terrible never deceive: The state in which they leave us is always one of enlightenment. And only this condition of vicious insight allows us a full grasp of the world, all things considered, just as a frigid melancholy grants us full possession of ourselves. We may hide from horror only in the heart of horror.

/The Medusa, T. Ligotti/

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[24. Apr 2015|16:45]

mindbound
[Tags|, , ]
[Garastāvoklis: |awake]
[Mūzika |Funker Vogt - Maschine Zeit: Nothing To Include]

Never write non-trivial shell scripts. As soon as you need a conditional or a loop, switch to Python.
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[24. Apr 2015|15:55]

mindbound
[Tags|, , , , , , ]
[Garastāvoklis: |working]
[Mūzika |Die Sektor - To Be Fed Upon: Through Glass]

Pirmoreiz veikta CRISPR/Cas9 intervence cilvēku embrijiem (kontrastā ar visām ĶTR daudzajām problēmām politiskā, ekonomiskā, cilvēktiesību u.c. plānos, izsaku cieņu turienes pētnieciskajiem institūtiem par neļaušanos tikt bremzētiem no politikas un retorikas puses (pie tam, kā redzams rakstā, pētniecība notiek uz non-viable embrijiem, iegūtiem no IVF klīniku atbiruma, kas, vismaz pagaidām, novērš arī problēmas ar pāragru tehnoloģiju ieviešanu klīniskajā apritē)). No vienas puses, šis sasniegums iezīmē jauna veida precīzas un detalizēti kontrolējamas gēnu terapijas ēras sākumu, taču, kā tas nereti mēdz būt, medaļas otra puse ir vismaz tikpat interesanta.

You can argue that it could be hugely beneficial to correct genetic diseases, but on the other hand we don’t know it's safe and it's a slippery slope. How long will it be before people try to alter eye and hair colour, and height and intelligence?

Most likely (not to say hopefully) not too long at all.

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[24. Apr 2015|00:41]

mindbound
[Tags|, , ]
[Garastāvoklis: |awake]
[Mūzika |Dernière Volonté - Devant Le Miroir: Douce Hirondelle]

Aldebaran is burning bright, the Old Ones grow restless, in places beyond and betwixt.

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Lai veicas [23. Apr 2015|22:45]

ctulhu
Laba ziemas svētku dāvana - jauns ķermenis

http://www.delfi.lv/news/world/other/video-virietis-krievija-gatavojas-galvas-transplantacijai-uz-cita-kermena.d?id=45878359
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[22. Apr 2015|19:59]

mindbound
[Tags|, ]
[Garastāvoklis: |awake]
[Mūzika |Millipede - A Mist And A Vapor: In The Blink Of An Eye]

Šonakt — lirīdu meteoru plūsma, maksimums 2300 UTC/0200 EET + DST. Jaunajā vietā ir pietiekami laba tumsa, lai kaut ko varbūt pat ieraudzītu.

Update: Neko neieraudzīju, sasodītie mākoņi.

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[21. Apr 2015|22:53]

mindbound
[Tags|, , , , ]
[Garastāvoklis: |working]
[Mūzika |Atrium Carceri - Void: Reselected]

The "write until you drop, resume writing upon getting back up again" regime seems to be working fine; keeps unwelcome thoughts at bay, too.
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Data acquisition bottleneck joprojām [21. Apr 2015|13:18]

ctulhu
Nupat mums prof. Volker Dotsch no Frankfurtes stāstīja par membrānas proteīnu ( nu arī receptoru tātad) NMR un pēc tam par in-cell NMR. Spektri ir ugly, jo tur viss interactojas un tad viņi taisa visādus hitrus labellingus lai tos vienkāršotu. Un tad es padomāju - -196gradC temperatūrā interakcijām vajadzētu būt vismaz daļēji nost. Protams cietu vielu NMR ir atsevišķa opera, tik tāds sīkums - vitrificēts materiāls jau pēc būtības nav cieta viela bet pāratdzesēts šķidrums..... jāpadomā, kā zināms štirlics padomāja un viņam iepatikās.
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[21. Apr 2015|11:51]

mindbound
[Tags|, , ]
[Garastāvoklis: |working]
[Mūzika |Murcof - Martes: Unison]

Non-GMO sweet potatoes contain bacterial DNA. How did it get there? Traditional farming.
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[20. Apr 2015|22:01]

mindbound
[Tags|, , , , ]
[Garastāvoklis: |working]
[Mūzika |Deied - Poisoned Wisdom: I Am The Center]

Nu jau kuro nakti pavadu kopā ar Džūliju un mums klājas labi.
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[20. Apr 2015|20:44]

mindbound
[Tags|, , , , ]
[Garastāvoklis: |awake]
[Mūzika |Tenhi - Maaäet: Sarastuskävijä]

Kā virs zemes, tā arī debesīs cilvēki atzinīgi novērtē kafijas krājumu papildināšanos.

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[20. Apr 2015|17:16]

mindbound
[Tags|, , , , ]
[Garastāvoklis: |awake]
[Mūzika |Autoclav1.1 - Embark On Departure: This Could Be You]

Paturēšanai redzes lokā.

Pagaidām gan nav daudz evidences, kas liktu prognozēt šāda gājiena izdošanos, taču tik un tā, frāze "politisko partiju un baznīcas tiešā kontrolē nokļūs sabiedriskie mediji" nav tā, ko es vēlētos lasīt ārpus orveliski distopiskas daiļliteratūras (un vēl jo vairāk pašreizējā "tikumības kampaņas" kontekstā).

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[19. Apr 2015|13:58]

mindbound
[Tags|, , , , , ]
[Garastāvoklis: |awake]
[Mūzika |Deied - Poisoned Wisdom: I Am The Center]

Šogad (līdz šodienai ieskaitot) pagūts izlasīt 14 grāmatas (tehniskas – 5, daiļliteratūras – 9), aptuveni 30 papīrus un vismaz dažpadsmit megabaitu koda. So far so good.
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[18. Apr 2015|23:42]

mindbound
[Tags|, , , , ]
[Garastāvoklis: |awake]
[Mūzika |Triarii - Muse In Arms: Birth Of A Sun]

The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. My learned colleagues in various fields, Dr McMenamin among them, continue to deny the implications of their discoveries. Even in the face of the incontrovertible evidence that they themselves have found, they still babble weakly of "ancient primitive cephalopods" and "midden heaps", as their frail minds refuse to acknowledge the truth and take refuge instead in these puerile protective fictions. Ancient, yes, ancient indeed was the creature that placed those bones, arranging them in patterns eerily reminiscent of certain petroglyphs reported by the survivors of the Arkham University Antarctic Expedition, immemorial carvings that are said to have driven more than one observer instantly insane with their blasphemous wrongness. Nor is Dr McMenamin wrong when he describes the maker of these patterns as "the most intelligent invertebrate ever", but it would certainly blast his mind with horror to know the full scope of that ravening, inhuman intellect. The Kanakas of the Pacific and certain degenerate islanders from the coast of Newfoundland might set Dr McMenamin straight on that score, but he would hardly think to consult them on the subject.

But I must not be too harsh in my judegments of these well-intentioned scholars. I remind myself that they have not had access to certain sources of information. The name of the terrible Cthulhu cult means nothing to them, nor have they spoken, as I have, with a detective of Yoknapatawpha County of Mississippi, who saw things in the swamps there that left him weak in mind and body, aged before his time. Nor have they ever looked into the writings of the mad Arab Abd al-Hazred, the terrible Necronomicon. If they had, certain things would become hideously clear to them, as they are to me.

Citiem vārdiem, ģeoloģijas profesora M. Makmenamina 2011. g. izvirzītā hipotēze, ka izmiruši milzu galvkāji varētu būt nodarbojušies ar pašportretiem. Ņemot vērā ļoti nelielo pieejamās evidences daudzumu un kopumā nelabvēlīgo prioru (pie mūsdienu galvkājiem šāda veida uzvedība nav tikusi novērota, kā arī nav atrastas paša hipotētiskā organisma kandidātfosīlijas), tas šobrīd ir visai mazvarbūtīgi un daudz ticamāka alternatīva hipotēze ir parasta pareidolija kombinācijā ar labi attīstītu iztēli, taču kā interesants (vismaz kuriozs) moments tas tik un tā šķita pieminēšanas vērts.

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[17. Apr 2015|22:57]

mindbound
[Tags|, , , ]
[Garastāvoklis: |blank]
[Mūzika |Art Of Empathy - Posthuman Decadence: Good Morning Sick World]

So fucking tired, it's like a week got compressed into a single day. Doesn't matter, progress has been made. Will have a drink and a book now.
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[17. Apr 2015|11:53]

mindbound
[Tags|]
[Garastāvoklis: |awake]
[Mūzika |Perturbator - Dangerous Days: Future Club]

Zerg are real (although tiny, not particularly threatening even in numbers, and without fleshy spaceship technology).
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[16. Apr 2015|21:27]

mindbound
[Tags|, , , , , , , ]
[Garastāvoklis: |awake]
[Mūzika |Rome - A Passage To Rhodesia: The River Eternal]

Says Peter Watts:

Evolution has no foresight. Natural selection only promotes what works in the moment. If a particular mutation doubles your reproductive rate, you will fill the world with thy numbers; the process doesn't understand too much of a good thing, doesn't care if greater fecundity today means overpopulation, starvation, and extinction tomorrow. All it cares about is whether the latest edit gives you an edge right now. Natural selection is the very incarnation of instant gratification (which, I've always thought, explains a great deal about human stupidity).

But what if we could build foresight into the system? What if you could force that gene onto the next generation, even if it reduced fitness in the classic sense? What if you could build code that would be beneficial over the long term, and ensure its spread even if it costs you in the moment? What if we could gift evolution with foresight? [What if we could introduce] engineered, virtually-unkillable genes into wild ecosystems to do our bidding?

It turns out we can do these things, and possibly much more.

Jā, tas atkal ir par CRISPR/Cas9, kas varētu izrādīties vismaz gadsimta svarīgākais sasniegums ģenētikā.

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[15. Apr 2015|22:58]

mindbound
[Tags|, , , , , ]
[Garastāvoklis: |awake]
[Mūzika |Hidden Place - Fantasia Meccanica: Window Sill]

Never doubt that sufficiently advanced technology can change the world. Indeed, it's the only thing that ever has.
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[15. Apr 2015|13:50]

mindbound
[Tags|, , , ]
[Garastāvoklis: |awake]
[Mūzika |Dernière Volonté - Devant Le Miroir: Verbes Fragiles]

Tādēļ vien, ka leviatāns ir mūžvecs, jau ilgstoši senils un pamazām tuvojas agonijai, noteikti nevajadzētu iedomāties, ka tā kustības vairs nevar nodarīt kaitējumu apkārtējiem. Tā arī četru Latvijas lielāko reliģisko veidojumu līderi ir spējuši pārkāpt savstarpējām teoloģiskajām domstarpībām un holier-than-thou attieksmei, lai vienotos kopīgā cīņā pret izglītību, kritisko domāšanu un ideju progresu.

Visi tie, kam šāda pozīcija un to balstošie argumenti šķiet atavistiski, kaitīgi gan esošajām, gan nākamajām paaudzēm un/vai bez sasaites ar novērojamo realitāti, tiek aicināti neklusēt.

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